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KMID : 0361020120550110736
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Korean Journal of Otolaryngology - Head and Neck Surgery
2012 Volume.55 No. 11 p.736 ~ p.739
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A Case of Spontaneous Resolution of Castleman’s Disease in the Neck
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Yun Seong-Hyun
Chae Soo-Ryang
Yoo Dong-Joon
Joo Young-Hoon
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Abstract
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Castleman’s disease, or angiofollicular lymph node hyperplasia, is a rare disorder that involves the proliferation of lymphoid tissue. The disease entity is classified into three pathologic subtypes, namely, the hyaline vascular, plasma cell, and mixed types; however, clinically, they are classified as unicentric and multicentric types. The former is treated primarily by excision, where-as systemic therapies have been used to treat the latter form, because of its more aggressive pattern. We report a case of a 17-year-old woman who underwent an excisional biopsy of one of the multiple affected cervical lymph nodes. A subsequent histopathologic examination revealed hyaline vascular Castleman’s disease. One month later, the disease spontaneously regressed and no recurrence was observed over a 12-month period following the excisional biopsy.
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KEYWORD
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Lymphoproliferative disorders, Neck, Spontaneous remission
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